I use cannabis for relief of numerous symptoms caused by my bone marrow cancer, myelofibrosis (anyone else with MF here?) The funniest thought came through my head, though you have to understand the endocannabinoid system for it to make sense. I am very allergic to yellow jackets. I stepped...
An endocannabinoid enhancer (eCBE) is a type of cannabinoidergic drug that enhances the activity of the endocannabinoid system by increasing extracellular concentrations of endocannabinoids.
An example of an actual eCBE is AM404, the active metabolite of the analgesic Paracetamol...
Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation
Sumner H. Burstein and Robert B. Zurier
AAPS J. 2009 March
This review covers reports published in the last 5 years on the anti-inflammatory activities of all classes of cannabinoids, including phytocannabinoids...
Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB1 and TRPV1 receptors
Maria Grazia Morgese, Tommaso Cassano, Vincenzo Cuomo, and Andrea Giuffrida
Exp Neurol. 2007 November
Levodopa is the most commonly prescribed drug for Parkinson's...
Cannabinoids and the Endocannabinoid System
The human body possesses specific binding sites on the surface of many cell types for cannabinoids, and our body produces several endocannabinoids, fatty acid derivatives that bind to these...
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
G. Gobbi, F. R. Bambico, R. Mangieri, M. Bortolato, P. Campolongo, M. Solinas, T. Cassano, M. G. Morgese, G. Debonnel, A. Duranti, A. Tontini, G. Tarzia, M. Mor, V. Trezza, S. R...