420 Girls - Sara Munoz and Anna Germain

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Cannabinoids are a large family of chemicals related to delta-9-tetrahydrocannabinol (THC), marijuana's main psychoactive (mind-altering) ingredient. Besides THC, the marijuana plant contains over 100 other cannabinoids. Scientists and manufacturers of "designer" drugs have also synthesized numerous cannabinoids in the laboratory (some of which are extremely potent and, when abused, have led to serious health consequences). The body also produces its own cannabinoid chemicals (called endocannabinoids), which play a role in regulating pleasure, memory, thinking, concentration, movement, coordination, sensory and time perception, appetite, and pain. - Sara Munoz (left), 21, of Mt. Morris, Michigan, and dispensary owner Anna Germain, 28, of Davison, Michigan