Smokin Moose
Fallen Cannabis Warrior & Ex Moderator
6 new Cannabinoids
(±)-6,7-trans-epoxycannabigerolic acid,
(±)-6,7-cis-epoxycannabigerolic acid,
(±)-6,7-cis-epoxycannabigerol,
(±)-6,7-trans-epoxycannabigerol,
5?-methyl-4-pentylbiphenyl-2,2?,6-triol,
7-methoxycannabispirone,
https://www.thieme-connect.com/ejour.../s-2008-1034311
Isolation and Characterization of New Cannabis Constituents from a High Potency Variety
Mohamed M. Radwan1, Samir A. Ross1,2, Desmond Slade1, Safwat A. Ahmed1, Fazila Zulfiqar1, Mahmoud A. ElSohly1,3
1 National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, USA
2 Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS, USA
3 Department of Pharmaceutics, School of Pharmacy, The University of Mississippi, University, MS, USA
Abstract
Phytochemical investigation of a high potency variety of Cannabis sativa L. resulted in the isolation of six new metabolites, (±)-6,7-trans-epoxycannabigerolic acid (2), (±)-6,7-cis-epoxycannabigerolic acid (3), (±)-6,7-cis-epoxycannabigerol (4), (±)-6,7-trans-epoxycannabigerol (5), 5?-methyl-4-pentylbiphenyl-2,2?,6-triol (7), and 7-methoxycannabispirone (8), along with seven known compounds namely, cannabigerolic acid (1), 5?-methoxycannabigerolic acid (6), cannabispirone (9), ?-cannabispiranol (10), dehydrocannabifuran (11), cannflavin B (12) and cannabigerol (13). The antimicrobial as well as the antileishmanial activities were investigated.
(±)-6,7-trans-epoxycannabigerolic acid,
(±)-6,7-cis-epoxycannabigerolic acid,
(±)-6,7-cis-epoxycannabigerol,
(±)-6,7-trans-epoxycannabigerol,
5?-methyl-4-pentylbiphenyl-2,2?,6-triol,
7-methoxycannabispirone,
https://www.thieme-connect.com/ejour.../s-2008-1034311
Isolation and Characterization of New Cannabis Constituents from a High Potency Variety
Mohamed M. Radwan1, Samir A. Ross1,2, Desmond Slade1, Safwat A. Ahmed1, Fazila Zulfiqar1, Mahmoud A. ElSohly1,3
1 National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, USA
2 Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS, USA
3 Department of Pharmaceutics, School of Pharmacy, The University of Mississippi, University, MS, USA
Abstract
Phytochemical investigation of a high potency variety of Cannabis sativa L. resulted in the isolation of six new metabolites, (±)-6,7-trans-epoxycannabigerolic acid (2), (±)-6,7-cis-epoxycannabigerolic acid (3), (±)-6,7-cis-epoxycannabigerol (4), (±)-6,7-trans-epoxycannabigerol (5), 5?-methyl-4-pentylbiphenyl-2,2?,6-triol (7), and 7-methoxycannabispirone (8), along with seven known compounds namely, cannabigerolic acid (1), 5?-methoxycannabigerolic acid (6), cannabispirone (9), ?-cannabispiranol (10), dehydrocannabifuran (11), cannflavin B (12) and cannabigerol (13). The antimicrobial as well as the antileishmanial activities were investigated.
