Jacob Bell
New Member
Robbins MS, Tarshish S, Solomon S, Grosberg BM.
Source
Montefiore Headache Center, Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Abstract
Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief. The beneficial effect may be related to the high concentration of cannabinoid receptors in the hypothalamus, which has been implicated as a site of dysfunction in neuroimaging studies of patients with cluster headache.
Comment in
Headache. 2011 Mar;51(3):502-5.
PMID:
19220500
[PubMed - indexed for MEDLINE]
Source: Cluster Attacks Responsive to Recreational Cannabis and Dronabinol
Source
Montefiore Headache Center, Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Abstract
Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief. The beneficial effect may be related to the high concentration of cannabinoid receptors in the hypothalamus, which has been implicated as a site of dysfunction in neuroimaging studies of patients with cluster headache.
Comment in
Headache. 2011 Mar;51(3):502-5.
PMID:
19220500
[PubMed - indexed for MEDLINE]
Source: Cluster Attacks Responsive to Recreational Cannabis and Dronabinol
