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Poor Diet Impairs Cannabinoid Receptors

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New data suggests that our diet can effect our response to cannabinoids. The authors demonstrate that an Omega-3 deficient diet in rats leads to a less functional endocannabinoid system, specifically by reducing the functionality of the Cannabinoid type 1 receptor (CB1R). The reduction of CB1Rs was associated by the authors with impaired emotional behavior. The endocannabinoid system may require a diet rich in Omega-3 fatty acids (i.e. Fish, nuts,etc).

Additionally, this article discusses the lack of essential nutrients in western diets. In the United States high-calorie, inexpensive, high-fat and nutritionally deficient diets are common. These bad diets are correlated to obesity and brain disease. For example, an imbalance in Omega-3 fatty acids has been linked to nueropsychiatric diseases, like depression. However the mechanism of neuroprotection from Omega-3 fatty acids remains unknown.
We already know that our diet can influence our response to cannabinoids and Cannabis. Could the negative effects of cannabinoids be related to nutritionally-deficient diets, which are also associated with mental diseases, such as depression? Could eating a better diet make for a better cannabinoid experience? This study raises a number of radical ideas that warrant further studies.

Source: Poor Diet Impairs Cannabinoid Receptors
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