I agree. This makes more sense.Did I get it right this time?
Decarbing For Maximum Neutral Cannabinoids (~ 95% conversion)
High CBD chemovar (strain)
Heat 15 minutes @ 221° F (105° C) to dry.
Continue heating either
* 60 minutes @ 248° F (120° C)
* 30 minutes @ 284° F (140° C)
Large Batch (larger than 4 oz)
* 15 minutes @ 221° F (105° C) to dry
* Continue 55-90 min @ 293° F (145° C)
High THC chemovar (strain)
Heat 15 minutes @221° F (105° C) to dry
Continue heating for either
* 60-120 minutes @ 248° F (120° C)
* 110 minutes @ 230°F (110° C)
Large Batch (larger than 4 oz)
*15 minutes @ 221° F (105° C) to dry
* Continue 45-55 min @ 293°F (145° C)
Mostly for making infused oils. I really don’t know if it matters (if it ruptures). I asked because someone else on 420 mentioned it and then I found the reference on the I love growing... site.Highya MedManMike,
Question - What's your purpose for decarbing? Does it matter whether it ruptures cell membrane? I only decarb before I use it for an edible; brownies, infused oil, etc.
Getting the most out of the product is pretty relative to the goals at the start. Couldn’t resist Mike.Mostly for making infused oils. I really don’t know if it matters (if it ruptures). I asked because someone else on 420 mentioned it and then I found the reference on the I love growing... site.
Just want to get the most out of the product.
Lots of amazing information thank you guys for all the time and money you spend on research on these topics, not everyone has the resources to be able to do what you amazing folk have done and continue to due, some of it goes way over my head and I’ll do research or ask questions of the stuff I’m unsure of but in the meantime, a big thank you once again@InTheShed, I ran the experiment- the oven won by a wide margin, but that’s not all the story. Pictures and a full report will follow. A diversion stepped in.
I went on a study journey for another member and learned a couple important things:
- how the body decides to make a cannabinoid
- how THC acts to offset autoimmune expression
*BIG SIGH* These were primary questions I’ve been searching for decent answers to all along, and this morning @lazyfish dropped the link to LipidWeb and there was the explaination about eCBs, all laid out for me by William W. Christie.
It’s in response to a rise in intra-cellular calcium levels that the ECS creates 2-AG and anandamide. There are many, many other cannabinoids not being studied the way these two have been.
So the cell has too much calcium flowing in, and it’s too excited for the job at hand. The ECS creates endocannabinoids with the correct signal and calcium balance is restored.
Another fascinatingly interesting thing I learned here (among so many other delights!) - that it’s possible 2-AG can diffuse freely through membranes to reach the sites of activity.
Just stop and think about that for a moment.........
There are concentrations of 2-AG in the brain ~170 to 1000 times higher than anandamide.
2-AG is a precursor to other bioactive lipids.
God....I love this work! I need a good buzz!
It’ll take me days to understand all this.
Oh! The autoimmune response!
Well... I dropped the link above for Camaro, and reading it I learned that there are microRNAs whose job it is to tell the immune system, “Enough. We’re done.” by influencing gene expression - silencing them. In people with autoimmune disease the mRNAs are turned off and the genes they’d be silencing are over-expressed.
They found 13 mRNAs that we’re inflienced by THC, and one in particular that was more profoundly affected.
In the presence of THC mRNA -690 dramatically increase in number. Cool, eh?
I recently came to understand that there are microfibers in the the extracellular matrix capable of exerting sustained, constructing stress - a wrinkling of the ECM - effectively silencing some of the finer nerve receptors that tell the cell what’s going on out there.
When communications with the outside goes down, what’s a cell to do? I suspect a few get sick trying to wing it. It’s a beautifully complex system, isn’t it?
You're more than welcome Camaro. It costs very little to be curious. Lol! We'll keep looking, and if anything shows up you'll be the first to know. Most of this is way over my head too, the first dozen or so times through.Lots of amazing information thank you guys for all the time and money you spend on research on these topics, not everyone has the resources to be able to do what you amazing folk have done and continue to due, some of it goes way over my head and I’ll do research or ask questions of the stuff I’m unsure of but in the meantime, a big thank you once again
If you could see the confused brain cells when I first approach this subject Bode..... I've simply stuck at it over and over again until it started to make sense. Now it's getting easier to grasp, but many basic cellular functions and terminology still give my gray matter fits too. I can't even attempt to do this straight.Highya SweetSue,
I tried reading the post by lazyfish, but couldn't understand. It's fascinating stuff! I'd like to know about cellular biology, but need to start from square one, and not get high while trying. lol. I've been amazed at all the signaling by the ECS. Fun to learn about something I can understand, though. Cheers
One of the keys to success is the desire to use what we have for the benefit of others. There's a trap to that. One can begin to believe this is your purpose, and I no longer buy into the idea that we have a "purpose" beyond exploring more ways to express love and joyful expectation. We hone our craft and it seems the universe has us meet up with the people who can most benefit from our help, and from whom we can benefit from.I wish I had payed more attention in biology class in school and health class lol.. I’ve always been decent at growing the plant but I’ve never understood the whole breakdown of THCA and CBDA and getting the benefits from them. Finding ways to make the body uptake these things the easiest is what I strive for, while I’ve always enjoyed given people a good product to smoke, after having SO diagnosed with AI and mother with cancer, I want to switch over towards being a care giver like I have always wanted to do but this pushes me to want to even more, the thought of helping people is what drives me not soo much the money aspect of it