The Use Of Cannabis Does Not Influence The Efficacy Of Two Anti-Cancer Drugs, A Clinical Study FindsTo investigate whether the use of a cannabis tea influences the pharmacokinetics and thus the efficacy of anti-cancer drugs a clinical study with 24 cancer patients was conducted at a hospital in Rotterdam, The Netherlands. 12 patients received irinotecan (600 mg) and 12 patients received docetaxel (180 mg). Three weeks later the same patients received both drugs concomitant with cannabis (200 ml herbal tea with 0,2 gram cannabis with 18 per cent THC) for 15 consecutive days in one dose in the evening, starting 12 days before the second treatment.
Medicinal cannabis administration did not significantly influence the course of the concentration of the two anti-cancer drugs irinotecan and docetaxel. Researchers concluded that the "evaluated variety of medicinal cannabis can be administered concomitantly with both anticancer agents without dose adjustments."
(Source: Engels FK, de Jong FA, Sparreboom A, Mathot RA, Loos WJ, Kitzen JJ, de Bruijn P, Verweij J, Mathijssen RH. Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel. Oncologist 2007;12(3):291-300.)
Source: International Association for Cannabis as Medicine