I know I suffer from anxiety and depression and I do stop for awhile after trying a strain. Its almost a detox. I'll smoke a strain for a couple of weeks and then just stop to get it out of my system and then try a different strain. There definitely needs to be more studies on this issues and other medical issues.I've gone through the sensitization protocol and I understand the principle behind the "herbal holiday", in fact I recommend it all the time, but I can't make myself skip a day. I don't deal with depression, but I'd probably consider switching between strains before I'd consider taking a day off.
Does anyone else have any success with either taking that day off or, alternatively, toggling between strains, and if so, would you be willing to share your thoughts with us? The more information we share the better we can refine the process.