US Patent 6630507 - Cannabinoids As Antioxidants And Neuroprotectants

Julie Gardener

New Member
Cannabinoids As Antioxidants And Neuroprotectants​

US Patent 6630507 - Patent 6630507 Issued on October 7, 2003. Estimated Expiration Date: February 2, 2021.

Abstract

Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH3, and COCH3.
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Field of Sear

Patent References

2304669

(3S-4S)-7-hydroxy-Ɗ6 -tetrahydrocannabinols
Method for the production of 6,12-dihydro-6-hydroxy-cannabidiol and the use thereof for the production of trans-delta-9-tetrahydrocannabinol
NMDA-blocking pharmaceutical compositions
Neuroprotective pharmaceutical compositions of 4-phenylpinene derivatives and certain novel 4-phenylpinene compounds
Nitroxides as protectors against oxidative stress
Method of inhibiting oxidants using alkylaryl polyether alcohol polymers
NMDA-blocking pharmaceuticals
Certain tetrahydrocannabinol-7-oic acid derivatives
(3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them
Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
Use of cannabinoids as anti-inflammatory agents

Source: Cannabinoids as antioxidants and neuroprotectants - US Patent 6630507 Abstract
 
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