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Although new neurons (green) are routinely produced in the dentate gyrus (red, neurons of the dentate gyrus) of young animals (a, b), this phenomenon drastically disappears during ageing (c, d). A low, non-psychoactive dose of a synthetic endocannabinoid receptor agonist (WIN-55,212-2) for 3 weeks promoted neurogenesis again (e, f), thus demonstrating the potential of using cannabinoids in treating learning/memory deficits occurring during normal and pathological ageing.
Source: New neuron production can be increased in the hippocampus of aged rats following cannabinoid treatment
Source: New neuron production can be increased in the hippocampus of aged rats following cannabinoid treatment
