Cannabis Agonist Reduces Non-Hodgkin Lymphoma Tumor Growth, Says Study

Jacob Bell

New Member
Stockholm, Sweden: The administration of the cannabinoid agonist R(+)-MA halts the spread and growth of cancerous tumors in animals with non-Hodgkin lymphoma, according to preclinical data published in the February 2008 issue of the International Journal of Cancer. Investigators at the Karolinska Institute in Stockholm reported that mice treated with R(+)-MA experienced a 40 percent reduction in tumor weight.

"The anti-proliferative and proapoptotic (stimulated cell death) effects of cannabinoids make the endocannabinoid system a potential new therapeutic target for individualized therapy in lymphomas," authors concluded.

Earlier this year, the journal Cancer Research reported that the administration of cannabinoids halts the spread of a wide range of cancers, including prostate cancer, breast cancer, lung cancer, pancreatic cancer, and brain cancer.

NORML Deputy Director Paul Armentano has a review of pot's anti-cancer properties online at the Huffington Post.

"Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation," International Journal of Cancer, September 2008

InterScience:
Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation - Gustafsson - 2008 - International Journal of Cancer - Wiley Online Library

Molecular Cancer Therapeutics: Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells

Oncogene: Oncogene - Abstract of article: [Delta]9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo

American Assoc. for Cancer Research: Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress

PubMed article: A pilot clinical study of Delta9-tetrahydrocannabi... [Br J Cancer. 2006] - PubMed result

Huffington Post:
Paul Armentano: What Your Government Knows About Cannabis And Cancer -- And Isn't Telling You


Source: Cannabis Agonist Reduces Non-Hodgkin Lymphoma Tumor Growth, says study
 
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