Cannabinoid Hyperemesis Syndrome Inducing Acute Prerenal Failure

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Abstract
HISTORY AND CLINICAL FINDINGS:
A 36-year-old patient presented to the psychiatric clinic with presumed worsening of a chronic psychosis.
INVESTIGATIONS:
Laboratory values revealed acute renal failure and electrolyte imbalance. A further diagnostic work-up including urine analysis as well as abdominal und retroperitoneal sonography was normal. DIAGNOSIS, THERAPY AND CLINICAL COURSE: By exact history taking the clinical diagnosis of a cannabinoid hyperemesis syndrome (CHS) was established. Symptomatic treatment with intravenous fluids and electrolytes together with strict cannabis abstinence completely resolved all symptoms and normalized all pathologic values.
CONCLUSION:
Recreational use of cannabis is widespread. It may induce a widely unknown syndrome characterized by nausea, vomiting and crampy abdominal pain accompanied by frequent hot showers or bathing. This syndrome should be recognized as a potential cause of acute prerenal failure.

Source: [Cannabinoid hyperemesis syndrome induc... [Dtsch Med Wochenschr. 2011] - PubMed - NCBI
 
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