Jacob Bell
New Member
Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol)
Author(s) Gonzalez-Rosales F, Walsh D
Journal, Volume, Issue Journal of Pain and Symptom Management 1997;14(5):311-314
Major outcome(s) patients was treated with several antiemetic drugs, but it was not until dronabinol was added that the nausea and vomiting stopped
Indication Nausea/vomiting;Cancer;Cancer chemotherapy
Medication Delta-9-THC
Route(s) Oral
Dose(s)
Duration (days)
Participants 1 patient with nausea and vomiting after whole brain radiati
Design Uncontrolled case report
Type of publication
Address of author(s) Department of Hematology/Oncology, Cleveland Clinic Cancer Center, Cleveland Clinic Foundation, Ohio 44195, USA
Abstract
Four years following resection of a Clark's level IV malignant melanoma, a 50-year-old man developed widespred metastatic disease involving the liver, bones, brain, gastrointestinal mucosa, and lungs. One week after whole brain radiation therapy, he was admitted to the hospital for nausea, vomiting, and pain. He was treated with several antiemetic drugs, but it was not until dronabinol was added that the nausea and vomiting stopped. Dronabinol was an effective antiemetic used in combination with prochlorperazine in nausea and vomiting unresponsive to conventional antiemetics.
Source: Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol)
Author(s) Gonzalez-Rosales F, Walsh D
Journal, Volume, Issue Journal of Pain and Symptom Management 1997;14(5):311-314
Major outcome(s) patients was treated with several antiemetic drugs, but it was not until dronabinol was added that the nausea and vomiting stopped
Indication Nausea/vomiting;Cancer;Cancer chemotherapy
Medication Delta-9-THC
Route(s) Oral
Dose(s)
Duration (days)
Participants 1 patient with nausea and vomiting after whole brain radiati
Design Uncontrolled case report
Type of publication
Address of author(s) Department of Hematology/Oncology, Cleveland Clinic Cancer Center, Cleveland Clinic Foundation, Ohio 44195, USA
Abstract
Four years following resection of a Clark's level IV malignant melanoma, a 50-year-old man developed widespred metastatic disease involving the liver, bones, brain, gastrointestinal mucosa, and lungs. One week after whole brain radiation therapy, he was admitted to the hospital for nausea, vomiting, and pain. He was treated with several antiemetic drugs, but it was not until dronabinol was added that the nausea and vomiting stopped. Dronabinol was an effective antiemetic used in combination with prochlorperazine in nausea and vomiting unresponsive to conventional antiemetics.
Source: Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol)
