THC As An Antiemetic In Patients Treated With Cancer Chemotherapy

[Julie Gardener]

Delta-9-tetrahydrocannabinol (THC) As An Antiemetic In Patients Treated With Cancer Chemotherapy;
A Double-Blind Cross-Over Trial Against Placebo​

Kluin-Nelemans JC, Nelemans FA, Meuwissen OJATh, Maes RAA
Veterinary and Human Toxicology 1979

Abstract

A double-blind cross-over trial with delta-9-tetrahydrocannabinol (THC) and placebo was employed to test the antiemetic effect on nausea and vomiting after MOPP-therapy. Although THC had remarkable antiemetic effects, there side effects were severe. Most patients preferred the nausea and the vomiting after MOPP-therapy to the use of THC. A relation between the antiemetic action or the side-effects and the blood-level of THC could not be demonstrated.

Source: Clinical Studies and Case Reports