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Analgesic Effect Of Delta-9-Tetrahydrocannabinol

Julie Gardener

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Analgesic Effect Of Delta-9-Tetrahydrocannabinol​
Noyes R Jr, Brunk SF, Baram DA, Canter A
Journal of Clinical Pharmacology 1975


A preliminary trial of oral delta-9-tetrahydrocannabinol (THC) demonstrated an analgesic effect of the drug in patients experiencing cancer pain. Placebo and 5, 10, 15, and 20 mg THC were administered double blind to ten patients. Pain relief significantly superior to placebo was demonstrated at high dose levels (15 and 20 mg). At these levels, substantial sedation and mental clouding were reported.

Source: Clinical Studies and Case Reports
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