The Analgesic Properties Of Delta-9-Tetrahydrocannabinol And Codeine

[Julie Gardener]

The Analgesic Properties Of Delta-9-Tetrahydrocannabinol And Codeine​

Noyes R Jr, Brunk SF, Avery DAH, Canter AC
Clinical Pharmacology and Therapeutics 1975

Abstract

The administration of single oral doses of delta-9- tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild analgesic effect. At a dose of 20 mg, however, THC induced side effects that would prohibit its therapeutic use including somnolence, dizziness, ataxia, and blurred vision. Alarming adverse reactions were also observed at this dose. THC, 10 mg, was well tolerated and, despite its sedative effect, may analgesic potential.

Source: Clinical Studies and Case Reports