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Not necessarily. I've done it and ended up with some nice plants. I've also had a few hermie.I had a Hermie that I didn't notice, will the seeds that I get from it create more Hermies?
It’ll increase the likelihood of getting hermies but not all will herm. There may even be some solid stress resistant phenos in there but really it takes effort, you have to constantly monitor them for sacks.
The goal of my current grow was to get seeds. I tried to reverse the sex of a single branch of my plants and thought I'd failed. Later, I found these:
Pollen Sacks on Reversed Branch
Only two sacks opened, but I got hundreds of seeds, and cross pollinated several plants that I didn't want. My point is they are very easy to miss if you only have a few on one your plants.