That is much clearer but makes me ask another question. Why can't suppositories be used for NDD? Is there something about being processed by the liver that makes the cannabinoids more accessible to the brain?
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That is much clearer but makes me ask another question. Why can't suppositories be used for NDD? Is there something about being processed by the liver that makes the cannabinoids more accessible to the brain?
Hi shed, I could be wrong but I thought suppositories were non-psycho active which suggests the cannabinoids don’t get accessed by the brain at all... I’m fuzzzzy atm so maybe that’s hogwash .
Why don’t cannabis suppositories give you a head high?
When administered rectally, the plant medicine directly enters the bloodstream through the cell walls and goes directly into the body, which is quickly distributed through the vascular system. It is a direct application to the bloodstream, bypassing the liver. The liver is a key to getting high. THC travels through the liver to the brain to induce a head high. When smoked, it travels through the lungs to the villi, then on to the liver. When taking it orally, it makes its way to the liver through digestion. This method takes the longest because of the digestive process and the amount of travel it takes to get to the brain. In the brain, THC interacts with nerve receptors, causing euphoria. The bottom line: Cannabis suppositories allow for larger doses of plant medicine without the head high versus smoking and ingesting orally.
Day 1 of radiation......good luck today hun. Be good to yourself, I know you hear your body.So it is Sunday morning January 14th 2018 and I am going to start my capsules with my brain strain medicine.
I have set it up that the only treatment from the hospital is my brain radiation. This will start Monday 15th for five straight days. After that I will be radiation and chemo free for at least 30 days. This way we can really see the effects the brain medicine will have. I'm very excited as I have been added to this team of amazing individuals. I will be travelling to Atlanta to visit my twin sisters. This will give me some down time and allow me to really focus on my healing.
Keys to the healing sister. Loved learning about your time off to heal. I'm honoured to be a part of your journey. I've never met a stronger more deserving and more determined person.
High Lady G2,
I have much patience, no patients. Retired.
Actually, I'm looking forward to your Cannabis for the Brain protocol. I hope I don't fall off the pedestal. I have a heads down and keep on keeping on approach. Persistence and perseverance. Not much fanfare, lol.
I should probably ask that question in the Oil Study Hall thread. I thought the difference was whether the THC was converted into delta 11 something or other which was the euphoric element.
I found this at What You Need to Know About Using Cannabis Suppositories - Health | MERRY JANE
Day 1 of radiation......good luck today hun. Be good to yourself, I know you hear your body.
Theres our girl......did we mention we missed you during your week off!?
Theirs those crazy dosing calculations again......and I'm a math guy lol. Thank GOD you guys know how they work lol.
I also noticed too that you've explained the dosing schedule......even for me it's easy to follow......duhhh....lol.
So why the Mediterranean diet? Brain food?
As to the question of suppositories being effective for brain treatment, I offer KR's latest thoughts on the subject, pulled from Cajun's thread.
Originally posted by KingstonRabbi: "Second, I would take most of the cannabis oil as suppositories, mixed as biobombs. Gelcaps work very well as suppositories. This method has the high bioavailability an bypasses the liver so it can't metabolize THC. Some will still get to liver on 2nd pass through circulatory system, but competitive inhibition will continue to help here. It may seem odd to use a dosing method that's about as far from the brain as can be, but fact is that any medicine will have to travel in blood to get to brain. Properly inserted it will travel straight to heart, to the lungs and back, and then back out to body still untouched by liver, and much of that blood goes to the brain, so suppositories will still work well for your brother."
It's a common mistake to confuse lack of psychoactivity with effectiveness of THC once it's into the system. Over at Cajun's thread we're always telling people that our expectation, if you're dosing correctly and using methods of competitive inhibition, is that you won't be feeling intense psychoactivity. All cannabis is psychoactive. THC is simply moreso.
We simply have no firm data on what phytocannabinoids are doing in the body. I personally try to avoid making any limiting statements when I speak of the actions of the ECS and cannabinoid therapies. I believe much of the effectiveness of the regimen lies in the belief that it's going to work. Until I have evidence to the contrary I'm going with the successes we've documented in our own numbers to guide me.
, so when I read G2 and Amy G saying that they believed that suppositories were less useful for brain health, I felt like I needed more research.
Howdy folks! I'm back with a response from SweetSue over on the Cannabis Oil Study Hall. My interest in the subject of suppositories for brain health is that I intended to use them for that reason alone. I'm not looking for the euphoria or the high or the mood alteration that cannabis provides when metabolized by the liver, but I am interested in brain health.
While I understand that high CBD/low THC strains have little effect on mood, I was looking to bypass that completely using suppositories, so when I read G2 and Amy G saying that they believed that suppositories were less useful for brain health, I felt like I needed more research. As the scientific community is far behind on the subject (and in the US is prevented from studying it), we have any number of members on this site who have done research on their own (including G2) and experience with other patients, so I went looking for answers from them.
This is SweetSue's reply:
I just wanted to pass that along so that those hoping to use suppositories to administer the cannabis to their systems in order to heal their brains still have hope that it will work!
Thanks G2 for the forum to have this discussion!
High Lady G2,
I applaud your efforts with such a complete instruction manual for treating Alzheiimers. Magnificent job! I learned some things, too. For instance I didn't put it together about the apprehension. I saw alot of that. I was thinking through the whole read about using Indica. You nailed that for sure. I think I'll go back and copy&paste to notepad to have a copy. I also thought - Sounds like most of the protocol is based on personal experience, mingled with professional opinions and research on a daily basis. Amazing position - to write a Cannabis-Alzheimers protocol as an Alzheimers patient. Can't refute your testimony to cannabis treatments!!
There is so much I wanted to say, but the protocol page is on page 12, so I'll read it again tomorrow and generate some more supportive comments tomorrow night.
You know, I'm really liking your courage, and willingness to fight this horrible disease! Your story is one for the tabloids, but being a part of your treatment process, and sharing so much love to those concerned is really heartwarming. And for that, I thank you!!
I just have to do this, sorry - I never actually said that I believed that. G suggested it in her protocol, and you asked her why, and I speculated about why she would suggest that. I don’t know anywhere near enough about this to have that belief or to state it. PLease don’t think i’m being snippy - I just don’t want a statement attributed to me that I didn’t make, and wouldn’t make without doing a lot more research .
I will in the future highlight speculative comments more clearly ..
And I hope I'm not being snippy in replying!
I'm really sorry Amy. I didn't mean to misquote you. When you said: "I could be wrong but I thought suppositories were non-psycho active which suggests the cannabinoids don’t get accessed by the brain at all," I thought I was safe saying that you believed that to be true (pending refutation like everything else). It was the "which suggests" in your post that made me think that was your opinion.