Just remember to add an air make up , if your house is new & energy efficient pushing large volumes of air out side with out one, you will pull carbon monoxide down your furnace chimney
more folks should pay attention to that. my grow room exhaust reverses air flow on the furnace stack. we periodically check it to be safe.
it never used to be an issue, but i switched to a phresh filter with less obstruction, and it caused trouble. i don't run a control on that fan and it is bit large for what i need to exhaust. we changed things up a bit so the grow room pulls more air from elsewhere.