A pure sativa harvested at 55 days! That's the holy grail, no?pure sativa heritage of un-named parents. She went 55 days in flower
@Graytail posted a link to Caplan's paper hereWhere can we find Caplans work?
How To Use Progressive Web App aka PWA On 420 Magazine Forum
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A pure sativa harvested at 55 days! That's the holy grail, no?pure sativa heritage of un-named parents. She went 55 days in flower
@Graytail posted a link to Caplan's paper hereWhere can we find Caplans work?
Dead mice aside (or rather, dead half-mice), the biggest problem with the study, according to Project CBD, is that just like in the 1974 rhesus monkey study, the dosage administered was astronomically high.The breathless reporting in Forbes focuses on a single, flawed, preclinical study and exaggerates it to the point of falsehood… A close examination of the Molecules study reveals a Pandora’s box of strange statements, problematic publishing, and unreasonable experimental design. On the first page, the abstract makes a claim that is fundamentally impossible, stating that, with chronic administration of CBD, ‘75% of mice gavaged with 615 mg/kg developed a moribund condition.’ But there were only 6 animals that received this dose! One doesn’t need an advanced degree in science or math to recognize that something is amiss. Seventy-five percent of six equals 4.5.
The researchers explain away this mega-dosing by pointing to something called allometric scaling, which is basically a set of guidelines for estimating an equally potent dose of a substance for humans and other animals based on body weight and body-mass index.Scientists force-fed mice a single dose of CBD, ranging from the supposedly ‘low’ dosage of 246 mg/kg up to a mega-dose of 2460 mg/kg CBD… The maximum human dosage recommended for the CBD-isolate Epidiolex is 20 mg/kg, which is over 100x less than what the Little Rock researchers force fed their experimental mice.
And that really gets to the heart of the issue.MDPI, which publishes the journal Molecules, has been called a predatory publisher. MDPI has been criticized for publishing unsound articles… Even if such allegations are true, it doesn’t mean that good work can’t end up in one of MDPI’s 213 journals. But it underscores the importance of checking scientific work, rather than diligently repeating and amplifying whatever claims are presented.