I finally got time to go check this site out and there's much to be excited about. First off, there's a good explaination of what lecithin brings to the table and then just reading through the process got me thinking about a number of different things.

It's interesting to discover that the alcohol plays a central part in the formation of the liposomes. We need to take this into consideration.

Using a blender is out of the question, but I was thinking a small ultrasonic might work to form the liposomes. What we're doing is very different from the encapsulation of massive amounts of Vit C. We're working in much smaller volumes. I'm not certain about the temperature control mentioned. I believe this is to ensure that the lecithin granules would be properly dissolved. I don't think it applies here.

What does seem to apply is the process of agitating (which causes heat), cooling in the refrigerator and then repeating that process many times over a short period. I'm assuming this gives the liposomes time to develop. In our case, not being able to agitate with a blender, this step may be more important. This is why I was thinking the ultrasonic might be a valuable tool. The agitation is what increases the formation of the liposomes.

Interesting, and much to think on. Previous to reading this well-thought out process I was under the impression that one couldn't create liposomes in a home setting, to find someone who proved that yes, indeed, you could. I got really excited when I was reading this. My spidey sense was tingling like mad and my heart was beating a bit faster. :laughtwo: We may be on to something here. It's definately something we need to explore more in depth.

I ordered an ultrasonic cleaner from the rain forest. It should come today. I will be chopping my CBD Shark Shock in another week and will make capsules using this machine. In the mean time I made topical roll on pain oil that I will put in the machine to see if it will help reduce the separation. I will also use this machine to clean for reuse my tincture dropper bottles. I will get multi uses from this machine.
 
I finished listening to my course on treating depression and anxiety with cannabis, and I have to say, this was the first course I was disappointed in. For someone who professes to be a specialist in cannabis medicine with over 20 years working with veterans, it was shocking to me that I knew more than he apparently knew about the dosing of cannabis to treat these maladies.

How is this even possible? There's this deep-seated bias in the medical community against cannabis and it flavors everything they do. This obviously isn't all doctors working with cannabis, but I'm continually shocked, for instance, at the misinformation about CBD, and how the capsules we all take so much for granted apparently are being completely overlooked by the medical "professionals." I've yet to hear anyone in one of these courses even hint at the importance of lecithin in edibles and how it can potentially be a game-changer. It's like we're living some alternate reality.

It's not like we're the only community making these capsules. Go anywhere online and you'll find recipies we all share openly. It's not like anyone's trying to hide it. So why are the "professionals" ignoring it?

I'm having a hard time digesting this and coming away with a sense of equanimity. I've been at this for hours. I need to go to bed and give it another listen tomorrow. Maybe I'm missing something. I come away from this one feeling more isolated. When the lab rats are better informed................

Sue,
This is EXACTLY why I'm here asking your advice Sue. I paid for and took two highly recommended and not cheap courses concerning MM in an attempt to know more about treating my son. It was readily apparent the courses were not current, chocked full of conflicting conclusions, here-say and direct misinformation; it was very disappointing to say the least. Sue, you do know more about this than subject than many "teachers" that are getting a check and presenting the "crap". I'd bet you probably know more concerning MM than 95% of all registered MDs in the US.
You are awesome Sue, it's the entire situation that is so very sad, most especially the DEA today deciding to keep the plant a Schedule 1, just insane, it really pisses me off.

Keith
 
No one should actually be surprised by this. Crooked bastards, the lot of them.

I actually am surprised, I truly thought that it would be moved to II considering the number of states legislating medical use.
I am really pissed off about it, damn politicians and corporations, half of them probably celebrated their "victory" with a cocktail and a BigPharma Stock purchase. Karma should pay these aholes involved in keeping Cannabis a Schedule 1 substance Sorry, I very seldom wish bad things on anyone.
Freakin ... ok, rant over.
 
:circle-of-love: Maybe hey didn't want to dig deep.. I don't know... I read too in the 420 news letter that coconut oil is the best for using in capsules etc..

That depends on what you're using it for AngryBird. I actually recommend olive oil as the carrier, unless you're using it to treat liver cancer, or you're doing the capsules for recreational purposes, in which case you want coconut oil.

It's the structure of the carrier oil that determines where it gets absorbed into the system. In every case we're trying to do everything possible to assure the maximum number of available cannabinoids. So if you're using coconut oil, which as a medium-chained fatty acid will be sent to the liver for absorbtion, you want to be particularly diligent about using steps of competitive inhibition. The liver is the birthplace of the enzymes that metabolize delta-9 THC into 11-hydroxy THC. That gets you wonderfully high, but it negates the medicinal benefits of those valuable cannabinoids. The busier we can keep those enzymes while the THC molecules make their way through the liver the better for our medicinal dose.

If you're treating just about anything else you want a long-chained fatty acid that gets absorbed into the lymphatic system ahead of the First Pass. This way they don't have to fight their way through the liver until the second pass. Our hope is they would have found some cell receptors to activate before then. Olive oil may well be the best possible choice of the available players. There's medicinal value in the oil itself that gives you benefit way beyond the absorbtion assistance.
 
I ordered an ultrasonic cleaner from the rain forest. It should come today. I will be chopping my CBD Shark Shock in another week and will make capsules using this machine. In the mean time I made topical roll on pain oil that I will put in the machine to see if it will help reduce the separation. I will also use this machine to clean for reuse my tincture dropper bottles. I will get multi uses from this machine.

May I ask, what machine did you go with and what did you pay for it?
 
I actually am surprised, I truly thought that it would be moved to II considering the number of states legislating medical use.
I am really pissed off about it, damn politicians and corporations, half of them probably celebrated their "victory" with a cocktail and a BigPharma Stock purchase. Karma should pay these aholes involved in keeping Cannabis a Schedule 1 substance Sorry, I very seldom wish bad things on anyone.
Freakin ... ok, rant over.

I feel your frustration, as a parent trying to save your own child. My daughter was counting on steps that would remove her from the criminal class because she finally found a medication that her body responds to, and it's one her mother grows in a closet.

I pride myself on having only good intentions for everyone. It's the whole thrust of my being. This madness challenges me in ways I'm not comfortable with.

I thank you for your confidence in my ability to help others ferret out the information they desperately need to heal themselves and their loved ones. It appears I'll be doing this for many years. I'll certainly get better at it, another of my personality traits perfectly suited to the job.

All this needless suffering. So sad. So very sad.
 
From mr krips journal.
Figures directly from the CDC on numbers of deaths per year in the USA:

* Prescription Drugs: 237,485 + 5,000 traffic fatalities
* Tobacco: 600,000
* Alcohol: 88,013 + 16,000 traffic fatalities
* Cocaine: 4,906
* Heroin: 7,200
* Aspirin: 466
* Acetaminophen (Tylenol): 179
* Marijuana: 0, none, not a single fatal toxic overdose in all medical history and no significant statistical record of traffic problems.


Let's also not forget about the many uses and benefits of hemp, more reasons for big business/the government to keep it illegal as businesses like oil would get hit hard.


On a positive note, our friend we gave CCO to for back pain really likes it. She had scoliosis bad as a child and doctors put bracing made of titanium in her back which had deteriorated and cannot be removed so she suffers from considerable pain, doctors prescribe pain meds which she does not want to take. She asked my gf about MMJ and we had extra capsules so gave her some. Sue - you were right, we will be making more.

In an above post you mention olive oil is better than coconut oil except in cases of liver cancer. Is the process the same, just substitute coconut oil with olive oil?

:thanks::cco:
 
May I ask, what machine did you go with and what did you pay for it?

FoodKing Ultrasonic Cleaner Ultrasonic Cleaner Jewelry Ultrasonic Jewelry Eyeglass Commercial Industrial with Digital Heater Timer Basket (3 Liter) It was $107 and free Prime shipping.
On another note, most of the instructions I have found say to use lecithin granules, however Cajun says to use liquid lecithin. I trust what Cajun has to say. I am a curious sort though, so after much searching I found that the liquid soy is more oil soluble and the granules are more water soluble. Also I would never use soy lecithin, only sunflower lecithin.
 
I will use a small canning jar with the ultrasonic cleaner and see how that goes.

The jar can't sit on the bottom of the ultrasonic. You'll need some way to suspend it in the fluid. I'm excited. :laughtwo: I'll be waiting to hear your thoughts on the process.
 
From mr krips journal.


Let's also not forget about the many uses and benefits of hemp, more reasons for big business/the government to keep it illegal as businesses like oil would get hit hard.


On a positive note, our friend we gave CCO to for back pain really likes it. She had scoliosis bad as a child and doctors put bracing made of titanium in her back which had deteriorated and cannot be removed so she suffers from considerable pain, doctors prescribe pain meds which she does not want to take. She asked my gf about MMJ and we had extra capsules so gave her some. Sue - you were right, we will be making more.

In an above post you mention olive oil is better than coconut oil except in cases of liver cancer. Is the process the same, just substitute coconut oil with olive oil?

:thanks::cco:

It's exactly the same ween. I'm so glad to hear your friend found relief with the capsules. I'm amazed at how effective the capsules have become. I was speaking to my daughter today, expressing my frustration with the depression and anxiety course. One of the first things he mentions in the course is that you can treat mild depression and anxiety. He also advises against edibles.

We finally contained my daughter's severe anxiety and depression with a protocol of four olive oil and CCO capsules a day with vaping for breakthrough anxiety or depression. Those edible capsules we shouldn't be considering have relieved anxiety, depression, agoraphobia, PTSD, chronic sinus infection and pains in her hip and back she's dealt with since a fall down a flight of steps over a decade ago.

Pretty amazing for a plant that our federal government insists doesn't have any true medicinal value, eh?
 
The jar can't sit on the bottom of the ultrasonic. You'll need some way to suspend it in the fluid. I'm excited. :laughtwo: I'll be waiting to hear your thoughts on the process.

There is a basket that the pint jar fits in just fine. I put it on it's side. Now the jar is in the freezer and I will run it through another 60 minute cycle in the morning. This is just an experiment for the roll on pain oil to try to keep it from separating. I will make capsules after my harvest.
 
FoodKing Ultrasonic Cleaner Ultrasonic Cleaner Jewelry Ultrasonic Jewelry Eyeglass Commercial Industrial with Digital Heater Timer Basket (3 Liter) It was $107 and free Prime shipping.
On another note, most of the instructions I have found say to use lecithin granules, however Cajun says to use liquid lecithin. I trust what Cajun has to say. I am a curious sort though, so after much searching I found that the liquid soy is more oil soluble and the granules are more water soluble. Also I would never use soy lecithin, only sunflower lecithin.

The lecithin granules he used had 22% phosphatidyl choline, and his point was the liquid soy lecithin was deficient in this component. The liquid sunflower has a total of 38% phosphatidyls:
* phosphatidyl choline 19%
* phosphatidyl inositol 12%
* phosphatidyl ethanolamine 7%

I think that means we made the better choice.

I took the time to work out some formulations for the BioBomb capsules if you're interested Mighty Mouse. We substitute carrier oil for water, I kept the lecithin at a constant 15 ml and the alcohol at a steady 12%, as per the patent info from that site you linked. (I just realized they said 10-12% on the alcohol, so we have more play.) The variable is the carrier oil. I'd like your opinion on these, if you don't mind. I sometimes feel as though I'm stumbling in the dark, placing my faith in the cosmos to lead me to where I need to be.

This is just a start. I wanted to see if these made any sense to everyone. With our recipe the CCO is constant at 1 gram/ml, lecithin stays the same at 15ml and the alcohol stays between 10-12% of volume. The carrier oil is the big variable. So I played with some numbers. I think we can get away with the strongest solvent we can get. I'm not so concerned about that, although I recommend something as pure as you can get. The closer to pure alcohol the better.

20:1 ratio at 65 ml

CCO 2% 1 ml
Lecithin 23% 15 ml
Alcohol 11% 7 ml
Carrier oil 64% 41.6 ml

10:1 ratio at 55 ml

CCO 2% 1 ml
Lecithin 27% 15 ml
Alcohol 11% 6 ml
Carrier oil 60% 33 ml

5:1 ratio at 40 ml

CCO 2% 1 ml
Lecithin 38% 15 ml
Alcohol 10% 4 ml
Carrier oil 50% 20 ml


I have a problem with the alcohol, and it's that Cajun told me directly that the alcohol wasn't necessary. This doesn't mean I don't consider that he may not have known about this process, but he was emphatic about this point. We need to determine if the alcohol used with the Vit C process isn't because they're using water. So my question is whether it's a necessary addition with an oil base? I'm not certain yet what role the alcohol plays and how that translates over to what we're doing, if in fact it does.

The article was insistent that the alcohol was a major reason that the liposomes were created. In the patent info it says:

[0052]
In the cold process, the lipids are preferably completely, or mostly, solubilized in an aqueous solvent or in a solvent miscible with water, such as most alcohols. Where the liposome composition is for oral administration, the aqueous solvent is preferably one that is suitable for ingestion. In embodiments where the solvent in the cold process is an alcohol, it preferred that the final alcohol content in the final product is less than about 10-12 weight percent, based on the weight of the final product. Although alcohol is not essential to form a stable liposome product, it does appear to be helpful for making a translucent gel. Alcohol further has the benefit of serving as an effective preservative. The use of alcohol may also be helpful or effective for forming small liposomes in the size range of about 200-500 nm. Other aqueous solvents are suitable and known to those of skill in the art. However, some solvents may result in a more turbid appearance than compositions made with alcohol,


- Method of making liposomes, liposome compositions made by the methods, and methods of using the same
US 20120171280 A


So, how necessary would that alcohol be when we're using oils instead of water and capsules instead of drinking the solution?

Anyone have any thoughts about any of this?
 
It's been five weeks and the skin continues to heal. This past week I went to applying the cream to the skin before bed, instead of wearing it all day. I still put a small amount on my face and hands, because I'm still not drinking enough water :straightface: mane the skin is a bit dry, but the patches have become small, dry patches with no scaling at all.

image15710.jpeg


The redness on the one is just from sitting cross-legged on the floor. The skin is very close to being completely healed of the psoriasis. On both feet the only dry patch is right below and slightly to the front of the malleolus. I've grown very fond of this healing cream. :battingeyelashes: :love:

I'm stoked. I can't tell you how freeing it's been not to have those scaly patches on my face and hands. Between Callanetics sculpting my body into a younger version and my skin healing to a younger tone I feel like I'm not aging at all, but growing younger. :laughtwo:

 
The lecithin granules he used had 22% phosphatidyl choline, and his point was the liquid soy lecithin was deficient in this component. The liquid sunflower has a total of 38% phosphatidyls:
* phosphatidyl choline 19%
* phosphatidyl inositol 12%
* phosphatidyl ethanolamine 7%

I think that means we made the better choice.

I took the time to work out some formulations for the BioBomb capsules if you're interested Mighty Mouse. We substitute carrier oil for water, I kept the lecithin at a constant 15 ml and the alcohol at a steady 12%, as per the patent info from that site you linked. (I just realized they said 10-12% on the alcohol, so we have more play.) The variable is the carrier oil. I'd like your opinion on these, if you don't mind. I sometimes feel as though I'm stumbling in the dark, placing my faith in the cosmos to lead me to where I need to be.

This is just a start. I wanted to see if these made any sense to everyone. With our recipe the CCO is constant at 1 gram/ml, lecithin stays the same at 15ml and the alcohol stays between 10-12% of volume. The carrier oil is the big variable. So I played with some numbers. I think we can get away with the strongest solvent we can get. I'm not so concerned about that, although I recommend something as pure as you can get. The closer to pure alcohol the better.

20:1 ratio at 65 ml

CCO 2% 1 ml
Lecithin 23% 15 ml
Alcohol 11% 7 ml
Carrier oil 64% 41.6 ml

10:1 ratio at 55 ml

CCO 2% 1 ml
Lecithin 27% 15 ml
Alcohol 11% 6 ml
Carrier oil 60% 33 ml

5:1 ratio at 40 ml

CCO 2% 1 ml
Lecithin 38% 15 ml
Alcohol 10% 4 ml
Carrier oil 50% 20 ml


I have a problem with the alcohol, and it's that Cajun told me directly that the alcohol wasn't necessary. This doesn't mean I don't consider that he may not have known about this process, but he was emphatic about this point. We need to determine if the alcohol used with the Vit C process isn't because they're using water. So my question is whether it's a necessary addition with an oil base? I'm not certain yet what role the alcohol plays and how that translates over to what we're doing, if in fact it does.

The article was insistent that the alcohol was a major reason that the liposomes were created. In the patent info it says:

[0052]
In the cold process, the lipids are preferably completely, or mostly, solubilized in an aqueous solvent or in a solvent miscible with water, such as most alcohols. Where the liposome composition is for oral administration, the aqueous solvent is preferably one that is suitable for ingestion. In embodiments where the solvent in the cold process is an alcohol, it preferred that the final alcohol content in the final product is less than about 10-12 weight percent, based on the weight of the final product. Although alcohol is not essential to form a stable liposome product, it does appear to be helpful for making a translucent gel. Alcohol further has the benefit of serving as an effective preservative. The use of alcohol may also be helpful or effective for forming small liposomes in the size range of about 200-500 nm. Other aqueous solvents are suitable and known to those of skill in the art. However, some solvents may result in a more turbid appearance than compositions made with alcohol,


- Method of making liposomes, liposome compositions made by the methods, and methods of using the same
US 20120171280 A


So, how necessary would that alcohol be when we're using oils instead of water and capsules instead of drinking the solution?

Anyone have any thoughts about any of this?

I do not have an answer for you as I also feel like I am stumbling in the dark. I am going to look into this much more. I usually make my CCO first and reclaim the alcohol and then make it into topical pain oil or capsules or brownies etc depending on what cut of the plant I am making the oil from. I am relatively new at this and only know enough to be dangerous, so I read a lot and experiment a lot. I do have folks that I have been making roll on topical pain oil for that keep asking for more. I am now branching out into tinctures and capsules for medical issues, but not cancer as I am not competent. More for relief from CP, MS, depression, and anxiety type of issues.
I learn a lot from what you share on the forums and have followed information you have shared. Thank you for taking on this calling, it has helped me a great deal.
 
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